Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris

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Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris

Purpose. We report the effect of isotretinoin on corneal topography, corneal thickness, and biomechanical parameters in patients with acne vulgaris. Method. Fifty-four eyes of 54 patients who received oral isotretinoin for treatment of acne vulgaris were evaluated. All patients underwent a corneal topographical evaluation with a Scheimpflug camera combined with Placido-disk (Sirius), ultrasonic...

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Systemic Isotretinoin for the Treatment of Acne

Oral isotretinoin (13-cis-retinoic acid) was first approved as treatment for severe acne by the US Food and Drug Administration (FDA) in 1982. To date the efficacy of isotretinoin has not been superseded by any other treatment and over two decades later isotretinoin remains the most clinically effective anti-acne therapy, producing long-term remission and/or significant improvement in many pati...

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Evaluation of seasonal variation in acne vulgaris

Background and Aim: Acne vulgaris is one of the most common skin diseases in adolescents and young adults. Although acne do not physically disable the patient, it can cause significant psychological morbidities. The disease etiology is not fully understood; however, there are several factors involved in the pathogenesis. The aim of this study is to investigate the seasonal variation of acne vul...

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Effects of Isotretinoin on bone density and Calcium homeostasis in patients with Acne Vulgaris

Background and aim: Side effects of long-term systemic isotretinion use with high accumulative doses on skeletal system have been known, but there are few studies about the effects of short term isotretinoin therapy for acne patients. This study was aimed to recognize the effects of systemic isotretinion on calcium homeostasis and bone density in acne patients referring to clinics affilia...

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ژورنال

عنوان ژورنال: Journal of Ophthalmology

سال: 2014

ISSN: 2090-004X,2090-0058

DOI: 10.1155/2014/701361